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(Pediatrics in Review. 2007;28:37-38.)
© 2007 American Academy of Pediatrics
In Brief |
| The first 20% of the full text of this article appears below. |
Screening for Retinoblastoma: Presenting Signs as Prognosticators of Patient and Ocular Survival. Abramson DH, Beaverson K, Sangani P, et al.
Pediatrics. 2003;112
:1248
1255
Retinoblastoma is a malignant tumor of the developing retina that usually occurs before 5 years of age. It is the most common pediatric eye tumor, occurring in about 1 in 20,000 children. When detected early, this embryonal tumor is among the most curable of childhood cancers. Early diagnosis and recognition of the possible genetic implications for the patient and family are important for optimal management and counseling. Delay in diagnosis can lead to the need for enucleation, central nervous system involvement, and hematogenous metastases.
Leukocoria, or a white pupillary reflex on the ophthalmoscopic "red reflex" test, is the most common presenting clinical finding, seen in 50% to 60% of cases of retinoblastoma. Parents are
William G. Wilson, MD
University of Virginia School of Medicine
Charlottesville, Va
Janet R. Serwint, MD, Consulting Editor, In Brief
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