Pediatrics in Review
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Depressant Substances in Adolescent Medicine

Robert L. DuPont MD1
Keith E. Saylor PhD2
 1 President, Institute for Behavior and Health, Inc, 6191 Executive Boulevard, Rockville, MD 20852; 301-231-9010
2 Director of Research, Institute for Behavior and Health, Inc, 6191 Executive Boulevard, Rockville, MD 20852; 301-231-9010

The benzodiazepines have replaced widespread use of barbiturates and other sedatives. They are effective, safe medicines used to treat a variety of disorders associated with excessive CNS excitability. Although many physicians avoid prescribing benzodiazepines to adolescents, there is little evidence to support this practice. Unless an adolescent has a history of substance abuse/dependence and suicidal ideation, the benzodiazepines are safe. Benzodiazepine toxicity rarely occurs unless another CNS depressant, especially alcohol, is used concurrently.






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Pediatrics Pediatrics in Review
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